| Pick | Rd | Team | Player | Pos | School | Age | G |
|---|---|---|---|---|---|---|---|
| 1 | 1 |
HOU
Houston Texans |
Mario Williams | DE | N.C. State | 21 | |
| 2 | 1 |
NOR
New Orleans Saints |
Reggie Bush | RB | Southern California | 21 | |
| 3 | 1 |
TEN
Tennessee Titans |
Vince Young | QB | Texas | 23 | |
| 4 | 1 |
NYJ
New York Jets |
D'Brickashaw Ferguson | T | Virginia | 22 | |
| 5 | 1 |
GNB
Green Bay Packers |
A.J. Hawk | LB | Ohio State | 22 | |
| 6 | 1 |
SFO
San Francisco 49ers |
Vernon Davis | TE | Maryland | 22 | |
| 7 | 1 |
OAK
Oakland Raiders |
Michael Huff | DB | Texas | 23 | |
| 8 | 1 |
BUF
Buffalo Bills |
Donte Whitner | DB | Ohio State | 21 | |
| 9 | 1 |
DET
Detroit Lions |
Ernie Sims | LB | Florida State | 21 | |
| 10 | 1 |
ARI
Arizona Cardinals |
Matt Leinart | QB | Southern California | 23 | |
| 11 | 1 |
DEN
Denver Broncos |
Jay Cutler | QB | Vanderbilt | 23 | |
| 12 | 1 |
BAL
Baltimore Ravens |
Haloti Ngata | DT | Oregon | 22 | |
| 13 | 1 |
CLE
Cleveland Browns |
Kamerion Wimbley | DE | Florida State | 22 | |
| 14 | 1 |
PHI
Philadelphia Eagles |
Brodrick Bunkley | DT | Florida State | 22 | |
| 15 | 1 |
STL
St. Louis Rams |
Tye Hill | DB | Clemson | 24 | |
| 16 | 1 |
MIA
Miami Dolphins |
Jason Allen | DB | Tennessee | 23 | |
| 17 | 1 |
MIN
Minnesota Vikings |
Chad Greenway | LB | Iowa | 23 | |
| 18 | 1 |
DAL
Dallas Cowboys |
Bobby Carpenter | LB | Ohio State | 23 | |
| 19 | 1 |
SDG
San Diego Chargers |
Antonio Cromartie | DB | Florida State | 22 | |
| 20 | 1 |
KAN
Kansas City Chiefs |
Tamba Hali | DE | Penn State | 22 | |
| 21 | 1 |
NWE
New England Patriots |
Laurence Maroney | RB | Minnesota | 21 | |
| 22 | 1 |
SFO
San Francisco 49ers |
Manny Lawson | DE | N.C. State | 22 | |
| 23 | 1 |
TAM
Tampa Bay Buccaneers |
Davin Joseph | G | Oklahoma | 22 | |
| 24 | 1 |
CIN
Cincinnati Bengals |
Johnathan Joseph | DB | South Carolina | 22 | |
| 25 | 1 |
PIT
Pittsburgh Steelers |
Santonio Holmes | WR | Ohio State | 22 | |
| 26 | 1 |
BUF
Buffalo Bills |
John McCargo | DT | N.C. State | 23 | |
| 27 | 1 |
CAR
Carolina Panthers |
DeAngelo Williams | RB | Memphis | 23 | |
| 28 | 1 |
JAX
Jacksonville Jaguars |
Marcedes Lewis | TE | UCLA | 22 | |
| 29 | 1 |
NYJ
New York Jets |
Nick Mangold | C | Ohio State | 22 | |
| 30 | 1 |
IND
Indianapolis Colts |
Joseph Addai | RB | Louisiana State | 23 | |
| 31 | 1 |
SEA
Seattle Seahawks |
Kelly Jennings | DB | Miami | 23 | |
| 32 | 1 |
NYG
New York Giants |
Mathias Kiwanuka | DE | Boston College | 23 |
★ = Pro Football Hall of Fame