| Pick | Rd | Team | Player | Pos | School | Age | G |
|---|---|---|---|---|---|---|---|
| 1 | 1 |
OAK
Oakland Raiders |
JaMarcus Russell | QB | Louisiana State | 22 | |
| 2 | 1 |
DET
Detroit Lions |
Calvin Johnson ★ | WR | Georgia Tech | 21 | |
| 3 | 1 |
CLE
Cleveland Browns |
Joe Thomas ★ | T | Wisconsin | 22 | |
| 4 | 1 |
TAM
Tampa Bay Buccaneers |
Gaines Adams | DE | Clemson | 24 | |
| 5 | 1 |
ARI
Arizona Cardinals |
Levi Brown | T | Penn State | 23 | |
| 6 | 1 |
WAS
Washington Redskins |
LaRon Landry | DB | Louisiana State | 22 | |
| 7 | 1 |
MIN
Minnesota Vikings |
Adrian Peterson | RB | Oklahoma | 22 | |
| 8 | 1 |
ATL
Atlanta Falcons |
Jamaal Anderson | DE | Arkansas | 21 | |
| 9 | 1 |
MIA
Miami Dolphins |
Ted Ginn Jr. | WR | Ohio State | 22 | |
| 10 | 1 |
HOU
Houston Texans |
Amobi Okoye | DT | Louisville | 20 | |
| 11 | 1 |
SFO
San Francisco 49ers |
Patrick Willis ★ | LB | Mississippi | 22 | |
| 12 | 1 |
BUF
Buffalo Bills |
Marshawn Lynch | RB | California | 21 | |
| 13 | 1 |
STL
St. Louis Rams |
Adam Carriker | DE | Nebraska | 23 | |
| 14 | 1 |
NYJ
New York Jets |
Darrelle Revis ★ | DB | Pittsburgh | 22 | |
| 15 | 1 |
PIT
Pittsburgh Steelers |
Lawrence Timmons | LB | Florida State | 21 | |
| 16 | 1 |
GNB
Green Bay Packers |
Justin Harrell | DT | Tennessee | 23 | |
| 17 | 1 |
DEN
Denver Broncos |
Jarvis Moss | DE | Florida | 23 | |
| 18 | 1 |
CIN
Cincinnati Bengals |
Leon Hall | DB | Michigan | 22 | |
| 19 | 1 |
TEN
Tennessee Titans |
Michael Griffin | DB | Texas | 22 | |
| 20 | 1 |
NYG
New York Giants |
Aaron Ross | DB | Texas | 24 | |
| 21 | 1 |
JAX
Jacksonville Jaguars |
Reggie Nelson | DB | Florida | 23 | |
| 22 | 1 |
CLE
Cleveland Browns |
Brady Quinn | QB | Notre Dame | 22 | |
| 23 | 1 |
KAN
Kansas City Chiefs |
Dwayne Bowe | WR | Louisiana State | 22 | |
| 24 | 1 |
NWE
New England Patriots |
Brandon Meriweather | DB | Miami | 23 | |
| 25 | 1 |
CAR
Carolina Panthers |
Jon Beason | LB | Miami | 22 | |
| 26 | 1 |
DAL
Dallas Cowboys |
Anthony Spencer | DE | Purdue | 23 | |
| 27 | 1 |
NOR
New Orleans Saints |
Robert Meachem | WR | Tennessee | 22 | |
| 28 | 1 |
SFO
San Francisco 49ers |
Joe Staley | T | Central Michigan | 23 | |
| 29 | 1 |
BAL
Baltimore Ravens |
Ben Grubbs | G | Auburn | 23 | |
| 30 | 1 |
SDG
San Diego Chargers |
Craig Davis | WR | Louisiana State | 21 | |
| 31 | 1 |
CHI
Chicago Bears |
Greg Olsen | TE | Miami | 22 | |
| 32 | 1 |
IND
Indianapolis Colts |
Anthony Gonzalez | WR | Ohio State | 22 |
★ = Pro Football Hall of Fame