| Pick | Rd | Team | Player | Pos | School | Age | G |
|---|---|---|---|---|---|---|---|
| 1 | 1 |
DET
Detroit Lions |
Matthew Stafford | QB | Georgia | 21 | |
| 2 | 1 |
STL
St. Louis Rams |
Jason Smith | T | Baylor | 23 | |
| 3 | 1 |
KAN
Kansas City Chiefs |
Tyson Jackson | DE | Louisiana State | 23 | |
| 4 | 1 |
SEA
Seattle Seahawks |
Aaron Curry | LB | Wake Forest | 23 | |
| 5 | 1 |
NYJ
New York Jets |
Mark Sanchez | QB | Southern California | 22 | |
| 6 | 1 |
CIN
Cincinnati Bengals |
Andre Smith | T | Alabama | 22 | |
| 7 | 1 |
OAK
Oakland Raiders |
Darrius Heyward-Bey | WR | Maryland | 22 | |
| 8 | 1 |
JAX
Jacksonville Jaguars |
Eugene Monroe | T | Virginia | 22 | |
| 9 | 1 |
GNB
Green Bay Packers |
B.J. Raji | DT | Boston College | 23 | |
| 10 | 1 |
SFO
San Francisco 49ers |
Michael Crabtree | WR | Texas Tech | 21 | |
| 11 | 1 |
BUF
Buffalo Bills |
Aaron Maybin | DE | Penn State | 21 | |
| 12 | 1 |
DEN
Denver Broncos |
Knowshon Moreno | RB | Georgia | 22 | |
| 13 | 1 |
WAS
Washington Redskins |
Brian Orakpo | LB | Texas | 23 | |
| 14 | 1 |
NOR
New Orleans Saints |
Malcolm Jenkins | DB | Ohio State | 21 | |
| 15 | 1 |
HOU
Houston Texans |
Brian Cushing | LB | Southern California | 22 | |
| 16 | 1 |
SDG
San Diego Chargers |
Larry English | LB | Northern Illinois | 23 | |
| 17 | 1 |
TAM
Tampa Bay Buccaneers |
Josh Freeman | QB | Kansas State | 21 | |
| 18 | 1 |
DEN
Denver Broncos |
Robert Ayers | DE | Tennessee | 24 | |
| 19 | 1 |
PHI
Philadelphia Eagles |
Jeremy Maclin | WR | Missouri | 21 | |
| 20 | 1 |
DET
Detroit Lions |
Brandon Pettigrew | TE | Oklahoma State | 24 | |
| 21 | 1 |
CLE
Cleveland Browns |
Alex Mack | C | California | 23 | |
| 22 | 1 |
MIN
Minnesota Vikings |
Percy Harvin | WR | Florida | 21 | |
| 23 | 1 |
BAL
Baltimore Ravens |
Michael Oher | T | Mississippi | 23 | |
| 24 | 1 |
ATL
Atlanta Falcons |
Peria Jerry | DT | Mississippi | 25 | |
| 25 | 1 |
MIA
Miami Dolphins |
Vontae Davis | DB | Illinois | 21 | |
| 26 | 1 |
GNB
Green Bay Packers |
Clay Matthews | LB | Southern California | 23 | |
| 27 | 1 |
IND
Indianapolis Colts |
Donald Brown | RB | Connecticut | 22 | |
| 28 | 1 |
BUF
Buffalo Bills |
Eric Wood | C | Louisville | 23 | |
| 29 | 1 |
NYG
New York Giants |
Hakeem Nicks | WR | North Carolina | 21 | |
| 30 | 1 |
TEN
Tennessee Titans |
Kenny Britt | WR | Rutgers | 20 | |
| 31 | 1 |
ARI
Arizona Cardinals |
Beanie Wells | RB | Ohio State | 21 | |
| 32 | 1 |
PIT
Pittsburgh Steelers |
Evander Hood | DE | Missouri | 22 |
★ = Pro Football Hall of Fame